Ivacaftor-elexacaftor-tezacaftor and tacrolimus combination in cystic fibrosis

Megan Smith,Kevin J Ryan,Hector Gutierrez, Luz Helena Gutierrez Sanchez, Janaina Nogueira Anderson,Edward P Acosta, Kim W Benner,Jennifer S Guimbellot

Journal of Cystic Fibrosis（2022）

引用 11|浏览9

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摘要

•Highly effective modulator treatment results in improvement in clinical outcomes.•Modulator use may result in drug interactions that need to be managed.•Tacrolimus and modulator use together is manageable.

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关键词

Ivacaftor,Tezacaftor,Elexacaftor,Liver transplantation,Tacrolimus,Drug interaction,Cytochrome p450,CFTR

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