Compositional and temporal changes of the gut microbiome in women with cervical cancer undergoing chemoradiation: Does it predict response?

Travis T. Sims,Lauren E. Colbert,Tatiana Karpinets,Greyson Willis Grossman Biegert,Andrea Y. Delgado,Melissa Paola Mezzari,Travis Solley,Kyoko Yoshida-Court,Aparna Mitra,Lilie L. Lin,Lois M. Ramondetta,Amir Anthony Jazaeri,Michael Frumovitz,Anuja Jhingran,Kathleen Schmeler,Jennifer Wargo,Ann H. Klopp

Gynecologic Oncology（2020）

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摘要

Objective: The gut microbiome may influence response to various cancer therapeutics, and its application in cervix cancer (CC) is lacking. This study aimed to assess the effect of chemoradiation (CRT) on the gut microbiome and to examine the association between the gut microbiome and clinical outcomes in women with CC undergoing CRT.

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Cervical cancer,Oncology,Medicine,Gut microbiome,Internal medicine

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