HCV resistance-associated substitutions following direct-acting antiviral therapy failure – Real-life data from Poland

Miłosz Parczewski,Ewa Janczewska,Arkadiusz Pisula,Dorota Dybowska,Władysław Łojewski,Adam Witor,Marta Wawrzynowicz-Syczewska,Łukasz Socha,Rafał Krygier,Brygida Knysz,Joanna Musialik,Anna Urbańska,Kaja Scheibe,Jerzy Jaroszewicz

Infection, Genetics and Evolution（2021）

引用 2|浏览5

暂无评分

摘要

•Resistance associated mutation to NS5A and NS3 agents are common among HCV directly acting antiviral failing patients.•Glecaprevir/pibrentasvir retained activity in majority of DAA failing patients.•The frequency of NS3, but not NS5A resistance substitutions decreases over time indicating reversal to drug susceptibility.

查看译文

关键词

HCV resistance,Resistance-associated substitutions,Directly acting antivirals

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要