Emergence of the E484K Mutation in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Lineage B.1.1.345 in Upstate New York

Emil Lesho,Brendan Corey,Francois Lebreton,Ana C Ong,Brett E Swierczewski,Jason W Bennett,Edward E Walsh,Patrick McGann

CLINICAL INFECTIOUS DISEASES（2022）

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摘要

A severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.1.345 variant carrying the E484K mutation was detected in 4 patients with no apparent epidemiological association from a hospital network in upstate New York. Subsequent analysis identified an additional 11 B.1.1.345 variants from this region between December 2020 and February 2021.

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关键词

E484K mutation, lineage B, 1, 1, 345, SARS-CoV-2

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