Association Between the Seed Storage Proteins 2S Albumin and 11S Globulin and Severe Allergic Reaction After Flaxseed Intake.

C Bueno-Díaz, C Biserni, L Martín-Pedraza,M de Las Heras,C Blanco, S Vázquez-Cortés,M Fernández-Rivas, E Batanero, J Cuesta-Herranz,M Villalba

Journal of investigational allergology & clinical immunology（2022）

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摘要

Seed storage proteins from flaxseed were involved in the development of severe symptoms in the 5 patients studied and exhibited cross-reactivity with other allergenic sources. Besides the severity of flaxseed allergy in patients sensitized to 2S albumin, this is the first time that 11S globulin has been identified as a potential allergen. Taking these data into account should ensure a more accurate diagnosis.

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关键词

11S globulin,2S albumin,Anaphylaxis,Cross-reactivity,Flaxseed,Food allergy

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