EPnet: A general network to predict enhancer-promoter interactions

Zihang Wang, Lin Zhou,Shuai Jiang,Wei Huang

2021 11th International Conference on Information Science and Technology (ICIST)（2021）

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摘要

The mechanism of spatio-temporal gene expression is significantly related to the interaction between the two regulatory elements on the DNA, enhancer and promoter. Identifying enhancer-promoter interactions that disrupt cell-specific gene expression and cause different human diseases remains to be a great challenge. To figure this out, we construct a sequence-based deep learning model, Enhancer-Pr...

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关键词

Deep learning,Information science,DNA,Genomics,Predictive models,Gene expression,Bioinformatics

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