Perampanel effectiveness and tolerability in patients with epilepsy at long-term follow-up

Mariana Fernandes,Filippo Dainese,Francesca Operto,Simona Lattanzi,Sara Matricardi,Rosaria Renna,Fabio Placidi,Francesco Paladin,Grazia Maria Giovanna Pastorino,Nicoletta Foschi,Elisabetta Cesaroni,Nicola Mercuri,Claudio Liguori

EPILEPSY & BEHAVIOR（2021）

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摘要

•No real-world studies have proved the very long-term effectiveness of Perampanel.•Perampanel showed a good effectiveness and tolerability at 24-month follow up.•Perampanel showed a good effectiveness both in pediatric and adult patients.•Early add-on of Perampanel may increase the chances of seizure freedom at follow up.

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PER,ASMs,MOA,AMPA,FOS,FU,AEs,SF

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