Targeted Truncation of the ADAM17 Cytoplasmic Domain in Mice Results in Protein Destabilization and a Hypomorphic Phenotype
Journal of Biological Chemistry（2021）
关键词
ADAM17 (a disintegrin and metalloprotease 17),TACE (TNFα converting enzyme),cell surface enzyme,membrane protein,protein stability,myeloid cell,knock-in mutation in mice
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