Intrinsic Cardiomyocyte Mitochondrial Defects Underlie Cardiac Dysfunction And Heart Failure Risk Associated With Hypoplastic Left Heart Syndrome

Xinxiu Xu,Tuantuan Tan,Jiuann-Huey Ivy Lin,Phillips Adams,Xiaoqin Liu,N. Feinstein Timothy,Omar Khalifa,George A. Porter,Sruti S. Shiva,Cecilia Lo

Circulation（2018）

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摘要

Introduction: Hypoplastic left heart syndrome (HLHS) is a complex congenital heart disease with high morbidity/mortality and high risk of heart failure. Based on findings from the Ohia HLHS mouse m...

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关键词

Hypoplastic left heart, Mitochondria, Stem cells, Congenital heart disease, Heart failure

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