The effect of axon trajectory on retinal ganglion cell activation with epiretinal stimulation

For epiretinal prostheses, disc electrodes stimulate retinal ganglion cells (RGCs) with electric current to create visual percepts. Prior studies have determined that the sodium channel band (SOCB), located on the RGC axon (30–50 µm from the soma), is the most sensitive site to extracellular stimulation because of its high sodium channel density. Biophysical cable models used to study RGC activati...