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Longitudinal Analysis Reveals That Delayed Bystander CD8+ T Cell Activation and Early Immune Pathology Distinguish Severe COVID-19 from Mild Disease

Laura Bergamaschi,Federica Mescia,Lorinda Turner,Aimee L. Hanson,Prasanti Kotagiri,Benjamin J. Dunmore,Helene Ruffieux,Aloka De Sa,Oisin Huhn,Michael D. Morgan,Pehuen Pereyra Gerber,Mark R. Wills,Stephen Baker,Fernando J. Calero-Nieto,Rainer Doffinger,Gordon Dougan,Anne Elmer,Ian G. Goodfellow,Ravindra K. Gupta,Myra Hosmillo,Kelvin Hunter,Nathalie Kingston,Paul J. Lehner,Nicholas J. Matheson,Jeremy K. Nicholson,Anna M. Petrunkina,Sylvia Richardson,Caroline Saunders,James E. D. Thaventhiran,Erik J. M. Toonen,Michael P. Weekes,Berthold Gottgens,Mark Toshner,Christoph Hess,John R. Bradley,Paul A. Lyons,Kenneth G. C. Smith

Immunity（2021）

引用 263|浏览38
关键词
SARS-CoV-2,COVID-19,bystander CD8+ T cell,recovery,immune pathology,systemic inflammation,complement,TNF-α,interferon
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