•We report 130 SARS-CoV-2 cases in people with CF (pwCF) to June 2020 across Europe.•Reported incidence was higher in pwCF versus the age-matched general population.•pwCF had more hospital and intensive care admissions than the general population.•Lung-transplanted pwCF had more severe illness and needed more care.•SARS-CoV-2 can cause severe disease in pwCF justifying priority vaccination.
