Integrating Prostate-specific Antigen Kinetics into Contemporary Predictive Nomograms of Salvage Radiotherapy After Radical Prostatectomy

Shauna R Campbell,Martin C Tom,Shree Agrawal,Jason A Efstathiou,Jeff M Michalski,Matthew C Abramowitz,Alan Pollack,Daniel E Spratt,Jason W D Hearn,Kevin L Stephans,Tianming Gao,Jianbo Li,Rahul D Tendulkar

European Urology Oncology（2022）

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摘要

The prostate-specific antigen (PSA) kinetics of a biochemical recurrence following radical prostatectomy, particularly PSA doubling time and pre–salvage radiotherapy (SRT) PSA, are strongly associated with adverse oncologic outcomes following SRT. Herein, we provide comprehensive nomograms in the ultrasensitive PSA era for the estimation of outcomes following SRT.

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关键词

Nomogram,Prostate-specific antigen doubling time,Salvage radiation,Prostate-specific antigen kinetics,Postprostatectomy outcomes

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