LMA was not superior to face-mask ventilation for neonatal resuscitation in term and later preterm infants born in Uganda

Study design: Superiority randomised controlled trial.\n\nAllocation: Cluster randomisation with face mask or laryngeal mask airway (LMA).\n\nBlinding: Unblinded.\n\nSetting: Single-site maternity hospital in Uganda.\n\nPatients: Babies born in hospital requiring positive pressure ventilation with gestational age of 34 weeks and weight of greater than 2 kg. Exclusion criteria include stillbirths and infants with major malformations affecting airways or incompatible with life.\n\nIntervention: Resuscitation by a midwife with face mask or LMA.\n\nOutcomes: The primary outcomes were neonatal intensive care unit (NICU) admission with moderate to severe hypoxic ischaemic encephalopathy (HIE) on days 1–5 of hospitalisation and composite of neonatal death within 7 days. The secondary outcomes included the need for advanced resuscitation, very early neonatal death within 24 hours of life, early neonatal death within 7 days, any hospital admission during …