Congenital self-healing reticulohistiocytosis in a neonate

A full-term 1-day-old boy was admitted to the neonatal intensive care unit for assessment of clustered purplish brown rashes on the right foot (figure 1A,B) since birth. There was no mucous membrane lesion, hepatosplenomegaly or lymphadenopathy. He was born by spontaneous vaginal delivery at 38+5 weeks of gestation to a healthy mother without perinatal infections. A punch biopsy revealed a dense infiltration of Langerhans cells with increased eosinophils in the …