Cover Feature: Conformational Preferences of Cyclopentane‐Based Oligo‐δ‐peptides in the Gas Phase and in Solution (ChemPlusChem 4/2021)

The Cover Feature shows the conformational preferences of oligomers of δ-amino acid (δAc5a) with a cyclopentyl constraint in the Cβ−Cγ bond of the backbone investigated by using DFT methods in the gas phase and in solution. In particular, the hexameric Ac-(δAc5a)6-NHMe preferentially adopted the mixed H16/14 helical structure in chloroform and the H14 helical structure in water. Pyrrolidine-substituted analogues also adopted helical structures. More information can be found in the Full Paper by H. S. Park and Y. K. Kang.