Midodrine, An Oral Alpha-1 Adrenoreceptor Agonist, Successfully Treated Refractory Congenital Chylous Pleural Effusion And Ascites In A Neonate

Satoshi Tamaoka,Asami Osada,Takane Kin,Takeshi Arimitsu,Mariko Hida

CHEST（2021）

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摘要

A trisomy 21 neonate presented with congenital chylous pleural effusion and ascites that was refractory to conventional pharmacotherapy. Midodrine, an oral alpha-1-adrenoreceptor agonist, achieved remission of chylous effusion without any adverse effects. To the best of our knowledge, this is the first neonatal case of successful management of congenital chylous pleural effusion and ascites with midodrine. CHEST 2021; 159(4):e189-e191

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congenital chylothorax, congenital chylous ascites, midodrine, neonate, trisomy 21

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