In Vitro Assessments Of Cytotoxic And Cytostatic Effect Of Two [Cu(Dien)(N-N)]Br-2 Complexes On L6, Hct, Pc3 And Hepg2 Cancer Cells

Two new Cu(II) complexes of type [Cu(dien)(N-N)] Br-2 (dien is diethlylenetriamine, C1 complex with N-N = diethlylenetriamine and C2 complex with N-N = propyl-1,3-diamine) were made valuable and in vitro screened for both cytostatic and cytotoxic activities against four cell lines: colon cancer (HCT), liver cancer (HepG2), prostate cancer (PC3) and as control cell (L6) human muscle cell was used via MTT test. The results reflected these complexes as a promising activity antiprolifrative agent against the used cell lines indicating that C1 and C2 complexes have a high anticancer activity at non-toxic concentrations.