A simple polysaccharide based injectable hydrogel compositing nano-hydroxyapatite for bone tissue engineering

Materials Letters(2021)

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摘要
•A simple polysaccharide injectable hydrogel was prepared based on Schiff base crosslinking.•Nano-hydroxyapatite could be uniformly composited in the hydrogel.•The composite hydrogel showed excellent compact bone repair effect.•The bone repair mechanism meets the concept of Guided Bone Regeneration (GBR).
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关键词
Biomaterials,Injectable hydrogel,Composite materials,Bone repair,Tissue engineering
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