A case of panuveitis and retinal vasculitis associated with pembrolizumab therapy for metastatic lung cancer

American Journal of Ophthalmology Case Reports(2021)

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摘要
We showed a case of retinal vasculitis occurred as an irAE of pembrolizumab for metastatic lung cancer. Retinal vasculitis was well managed with transient pembrolizumab discontinuation and oral corticosteroid therapy, and pembrolizumab was restarted with the aid of STTA. As ocular irAEs might be controlled by local corticosteroid therapy, the decision to continue immune checkpoint inhibitor therapy should be made on a case-by-case basis.
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关键词
Retinal vasculitis,Immune checkpoint inhibitor,Programmed death protein 1,Pembrolizumab,Immune-related adverse event
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