P35.23 Integrated Analysis of Genomic and Immunological Features in Lung Adenocarcinoma with Micropapillary Component

S. Zhang,Y. Xu, P. Zhao,H. Bao,X. Wang,R. Liu, R. Xu, J. Xiang,H. Jiang, J. Yan,X. Wu, Y. Shao,J. Liang,Q. Wu,Z. Zhang,S. Lu,S. Ma

Journal of Thoracic Oncology（2021）

引用 13|浏览18

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摘要

We identified multiple novel MPC-enriched genetic changes that could help us understand the nature of this aggressive cancer subtype. High MPC tumors tended to have elevated levels of TMBs, T cell infiltration, and immunosuppression than low MPC tumors, implying the potential link between MPC content and sensitivity to immunotherapy.

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关键词

transcription termination factor 1, micropapillary adenocarcinoma, tumor mutation burden

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