3k3a-Apc Restores Oligodendrocyte Pools In Models Of White Matter Stroke Via Par1 Signaling.

Angeliki M. Nikolakopoulou,Wang Yaoming,Dai Zhonghua,Mikko Huuskonen,Axel Montagne, Divna Lazic,Abhay Sagare,Zhao Zhen,John H. Griffin,Berislav Zlokovic

Stroke（2021）

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摘要

A recombinant variant of activated protein C, 3K3A-APC, was recently tested in a successful phase II clinical trial for ischemic stroke (RHAPSODY), which demonstrated that the treatment may reduce ...

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