Single-Cell Sequencing, An Advanced Technology In Lung Cancer Research

Hao Wang,Die Meng,Haoyue Guo,Chenglong Sun,Peixin Chen,Minlin Jiang,Yi Xu,Jia Yu,Qiyu Fang,Jun Zhu,Wencheng Zhao,Shengyu Wu,Sha Zhao,Wei Li,Bin Chen,Lei Wang,Yayi He

ONCOTARGETS AND THERAPY（2021）

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摘要

Single-cell sequencing (SCS) which has an unprecedentedly high resolution is an advanced technique for cancer research. Lung cancer still has a high mortality and morbidity. For further understanding the lung cancer, SCS is also been applied to lung cancer research to investigate its heterogeneity, metastasis, drug resistance, tumor microenvironment and many other issues. In this review, we summarized lung cancer research using SCS and their research achievements.

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关键词

single, cell sequencing, lung cancer, intratumoral heterogeneity, tumor microenvironment, lung cancer therapy

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