Impact of PTV margin reduction (2 mm to 0 mm) on pseudoprogression in stereotactic radiotherapy of solitary brain metastases.

Justine Badloe,Mirjam Mast,Anna Petoukhova, Jan-Huib Franssen, Elyas Ghariq, Noëlle van der Voort van Zijp,Ruud Wiggenraad

Technical innovations & patient support in radiation oncology（2021）

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摘要

PTV-margin reduction did not reduce the incidence of pseudoprogression in LINAC-based-SRT for single brain metastases. We did not find a significant association of GTV-PTV margin or V12Gy with the incidence of pseudoprogression in solitary metastases treated with a single fraction. LC rates were similar, indicating margin reduction seems to be safe.

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关键词

Brain metastases,Margins,Pseudoprogression,Stereotactic radiotherapy

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Impact of PTV margin reduction (2 mm to 0 mm) on pseudoprogression in stereotactic radiotherapy of solitary brain metastases.

Impact of PTV margin reduction (2 mm to 0 mm) on pseudoprogression in stereotactic radiotherapy of solitary brain metastases.