Morphological and transcriptomic alterations in neonatal lamb testes following developmental exposure to low-level environmental chemical mixture

•Developmental exposure to environmental chemical mixture affects testis development.•Adverse outcome can phenotypically resemble mixed testicular atrophy as seen in TDS.•Transcriptome analysis indicates differential expression in the mTOR signalling pathway.•Phenotypic variation is associated with distinctive gene expression profiles.•Susceptible and resistant phenotypes may be related to differential CREB activation.