Vitamin D pathway gene polymorphisms, vitamin D level, and cytokines in children with type 1 diabetes

Watip Tangjittipokin, Pichakorn Umjai,Khwanhatai Khemaprasit,Parichat Charoentawornpanich,Chutima Chanprasert,Nipaporn Teerawattanapong,Tassanee Narkdontri,Jeerunda Santiprabhob

Gene（2021）

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摘要

•A relationship between studied single nucleotide polymorphisms and T1D was found in CYP2R1 (rs10741657).•VDR haplotypes were different between T1D patients and controls.•Variations in DHCR7, CYP27B1, GC and VDR were associated with vitamin D and circulating cytokine levels in children with T1D.

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关键词

25OHD2,25(OH)D3,DHCR7,ALT,ALP,AST,BUN,CTLA-4,HbA1c,GC,hsCRP,HLA,INS,PTH,PTPN22,SNP,T1D,VDR

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