Cytotoxic tigliane diterpenoids from Euphorbia neorubella
NATURAL PRODUCT RESEARCH(2022)
摘要
Two new tigliane diterpenes, named eupneonoids A (1) and B (2), together with four known analogues (3-6) were isolated from the whole plant of Euphorbia neorubella Bruyns. Their structures were deduced based on the detailed spectroscopic analysis. All the isolates displayed cytotoxic effects against A549 human tumor cell lines with IC50 values ranging from 1.318 to 7.042 mu M.
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关键词
Euphorbia neorubella, tigliane diterpenoids, cytotoxicity
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