Temozolomide chronotherapy in patients with glioblastoma: a retrospective single-institute study.

Anna R Damato,Jingqin Luo,Ruth G N Katumba,Grayson R Talcott,Joshua B Rubin,Erik D Herzog,Jian L Campian

Neuro-oncology advances（2021）

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摘要

Our study presents preliminary evidence for the benefit of TMZ chronotherapy to GBM patient survival. This impact is more pronounced in MGMT-methylated patients.

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关键词

MGMT,chronotherapy,circadian,glioblastoma,temozolomide

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