A Mitochondria-Targeted Near-Infrared Fluorescent Probe For Imaging Viscosity In Living Cells And A Diabetic Mice Model

A mitochondria-targeted near-infrared fluorescent probe NIR-V with 700 nm emission was designed to monitor cell viscosity changes with high selectivity and sensitivity, which was applied to detect the intracellular viscosity and image pancreatic tissue in a diabetic mouse model. Probe NIR-V provides an effective way to diagnose viscosity related diseases.