Comparative diagnostic performance of rapid antigen detection tests for COVID-19 in a hospital setting

Bianca Bruzzone,Vanessa De Pace,Patrizia Caligiuri,Valentina Ricucci,Giulia Guarona,Beatrice M. Pennati,Simona Boccotti,Andrea Orsi,Alexander Domnich,Giorgio Da Rin,Giancarlo Icardi

International Journal of Infectious Diseases（2021）

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摘要

•Not all available rapid SARS-CoV-2 antigen tests have a sensitivity of ≥80/90%.•Sensitivity of rapid SARS-CoV-2 antigen tests is primarily driven by viral load.•Antigen test optimal sensitivity is at reverse transcription PCR cycle threshold ≤29.•Highly specific rapid tests are useful for screening in high incidence settings.

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关键词

COVID-19,SARS-CoV-2,Rapid antigen detection test,Italy

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