Lipid homeostasis and mevalonate pathway in COVID-19: Basic concepts and potential therapeutic targets

Maria Chiara Proto,Donatella Fiore,Chiara Piscopo,Cristina Pagano,Mario Galgani,Sara Bruzzaniti,Chiara Laezza,Patrizia Gazzerro,Maurizio Bifulco

Progress in Lipid Research（2021）

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摘要

Despite encouraging progresses achieved in the management of viral diseases, efficient strategies to counteract infections are still required. The current global challenge highlighted the need to develop a rapid and cost-effective strategy to counteract the SARS-CoV-2 pandemic.

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关键词

SARS-CoV-2,Lipid homeostasis,Viral infections,Cholesterol,Mevalonate pathway inhibitors,Statins

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