How Mutations In Ryr1 That Cause Malignant Hyperthermia Increase Ryr1 Sensitivity To Activators

Matthew L Baker,Robert T Dirksen,Susan L Hamilton

CELL CALCIUM（2021）

引用 0|浏览8

暂无评分

摘要

New electron cryomicroscopy structures of RYR1 show that mutations associated with Malignant Hyperthermia drive conformational changes in the cytoplasmic domains of the closed channel to more closely resemble those of the open channel.

查看译文

关键词

RYR1, Electron cryomicroscopy, Malignant hyperthermia

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要