Mini-Review: Induced pluripotent stem cells and the search for new cell-specific ALS therapeutic targets

•ALS disease heterogeneity presents challenges for therapeutic development.•Animal modeling has provided initial insights into cell subtype contributions to ALS.•iPSC show potential for dissecting contributions of cell subtypes to ALS progression.•3D modeling and precision medicine approaches with IPSC are powerful new platforms.•iPSC have helped identify drugs currently in clinical trial for ALS.