Knockdown of R-spondin1 leads to partial sex reversal in genetic female Chinese soft-shelled turtle Pelodiscus sinensis

General and Comparative Endocrinology(2021)

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摘要
•Rspo1 showed a dimorphic expression pattern through sex determination periods.•Rspo1 was rapidly downregulated during AI-induced female-to-male sex reversal.•Rspo1 loss of function led to partial female-to-male sex reversal in ZW turtles.
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关键词
Pelodiscus sinensis,R-spondin1,Ovarian differentiation,Sex reversal
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