High levels of Tim-3+Foxp3+Treg cells in the tumor microenvironment is a prognostic indicator of poor survival of diffuse large B cell lymphoma patients

Weijie Zhong,Xiudan Liu,Zhigang Zhu,Qingshan Li,Kangbao Li

International Immunopharmacology（2021）

引用 12|浏览8

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摘要

•High abundance of TFT cells in the TME is predictive of poor outcomes of DLBCL.•TFT cells promote DLBCL development partly by secreting IL-10 in the TME.•Anti-Tim-3 antibodies may present an effective therapeutic agent for DLBCL.

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关键词

Tim-3+Foxp3+Treg cells,Tim-3,Tumor microenvironment,Prognostic factors,Diffuse large B cell lymphoma

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