Serum untargeted metabolomics delineates the metabolic status in different subtypes of non-alcoholic fatty liver disease

Liyan Liu,Jinhui Zhao,Runan Zhang,Xuemei Wang,Yan Wang,Yang Chen,Rennan Feng

Journal of Pharmaceutical and Biomedical Analysis（2021）

引用 8|浏览6

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摘要

•A total of 5 metabolites were identified and composed diagnostic model for screening NAFLD.•There were some significant metabolic differences between Lean-/Obese-NAFLD.•The metabolism of amino acids and fatty acids played important roles in Obese-NAFLD and Lean-NAFLD, respectively.

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关键词

AA,AAA,AEA,AUC,BASO,BA,BCAA,BUN,BPI,CRE,CKD,CVD,DHEA,DHEA-S,EO,FBG,F-insulin,HCs,HCT,HDL-C,HGB,HMDB,HOMA-IR,IR,IS,KEGG,LDL-C,Log10(Value),LYMPH,lysoPC,NAFLD,NASH,NEUT,MONO,OPLS-DA,PAA,PBUTs,PCA,PS,PUFA,QC,RBC,RSD,ROC,RT,SA,SD,SS,TC,TG,UA,USFA,VIP,WAT,WBC

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