Monocyte To High-Density Lipoprotein Cholesterol Ratio Is Associated With The Presence Of Carotid Artery Disease In Acute Ischemic Stroke

BIOMARKERS IN MEDICINE(2021)

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摘要
Aim: Monocyte to high-density lipoprotein cholesterol ratio (MHR) has recently emerged as a predictor of cardio-cerebrovascular diseases. Since around one-fifth of strokes are linked to atherosclerosis carotid artery, we aimed to present the relationship between carotid artery disease (CAD) and MHR value in acute ischemic stroke (AIS). Materials & methods: A total of 209 adult AIS patients analyzed. Patients divided into two groups in respect to the existence of CAD. MHR was compared between the two groups. Results: MHR with a cut off of 17.23 predicted the presence of disease in the carotid artery, with a sensitivity of 91.9% and specificity of 66.7. MHR was the independent predictor for the presence of disease in the carotid artery. Conclusion: MHR was found to be an independent predictor for the CAD in AIS. Therefore, in AIS patients with high MHR value, CAD should be examined more carefully.
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关键词
acute ischemic stroke, atherosclerosis, carotid artery disease, inflammation, monocyte, monocyte-to-high-density lipoprotein ratio, MHR
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