DNA methylation as a key epigenetic player for hepatoblastoma characterization

Maria Rivas,Talita Aguiar,Gustavo Fernandes,Renan Lemes,Luiz Caires-Júnior,Ernesto Goulart,Kayque Telles-Silva,Mariana Maschietto,Monica Cypriano, Silvia de Toledo,Dirce Carraro, Isabela da Cunha,Cecilia da Costa,Carla Rosenberg,Ana Krepischi

Clinics and Research in Hepatology and Gastroenterology（2021）

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摘要

•Hepatoblastoma is a rare embryonal liver tumor occurring in the pediatric population.•DNA methylation machinery exerts a key role in the characterization of hepatoblastoma.•Our data propose that a panel of 13 genes can be used for hepatoblastoma stratification.

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关键词

HB,SIOPEL,COG,GRAACC,iPSC,CHIC,HCC,Epi-CA/CB,MRS-HB

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