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Neurodegenerative VPS41 Variants Inhibit HOPS Function and Mtorc1‐dependent TFEB/TFE3 Regulation

Reini E. N. van der Welle,Rebekah Jobling,Christian Burns,Paolo Sanza,Jan A. van der Beek,Alfonso Fasano,Lan Chen,Fried J. Zwartkruis,Susan Zwakenberg,Edward F. Griffin,Corlinda ten Brink,Tineke Veenendaal,Nalan Liv,Conny M. A. van Ravenswaaij-Arts,Henny H. Lemmink,Rolph Pfundt,Susan Blaser, Carolina Sepulveda,Andres M. Lozano,Grace Yoon,Teresa Santiago-Sim,Cedric S. Asensio,Guy A. Caldwell,Kim A. Caldwell,David Chitayat,Judith Klumperman

EMBO Molecular Medicine（2021）

Cited 27|Views38
Key words
Autophagy,HOPS complex,lysosome&#8208,associated disorder,mTORC1,TFEB,TFE3
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