A national trauma data bank analysis of large animal-related injuries

•Patients involved in a LARI are moderately injured with more complex injuries occurring in the chest, head, and lower extremities.•Fall from horse was the most common LARI mechanism.•Overall mortality was low.•Compared to non-riders, riders were more likely to sustain severe injuries to the chest and spine.•Severe injury patterns were similar when comparing riders to MVC; trauma teams should approach LARI as they would an MVC.