Phenotypes, Treatable Traits, Gold Groups And Grades - How They Predict Mortality Risk In Copd Patients? (Data From The Czech Multicenter Research Database Of Copd)

Introduction: Various characteristics (e.g. FEV1, BMI) or composite tools are used to asess prognosis in COPD patients. Some of these tools are time-consuming and may be unpractical for use in daily practice. Aims: Our aim was to analyze prognostic performance of COPD phenotypes, treatable traits and GOLD stages + groups in relation to long-term outcomes. Methods: We analyzed 5-year survival of 720 patients of the Czech Multicenter Research Database of COPD. Kaplan-Meier (KM) analysis was performed to estimate survival for Spanish phenotypes, Czech guidelines-defined treatable traits and GOLD stages + groups. Moreover, we performed a classification tree analysis to assess the role of confounders. Results: KM analysis showed GOLD stage IV (HR 2.42) and group D (HR 2.77) being associated with poor outcome (both p Conclusion: For a tentative prognosis assessment, careful description of COPD characteristics and comorbidities may be sufficient.