Synthesis, Crystal Structures, And Antimicrobial Activity Of Copper(Ii) Complexes Derived From N '-(1-(Pyridin-2-Yl)Ethylidene)Isonicotinohydrazide

Two mononuclear copper(II) compounds, [Cu(HL)(2)](ClO4)(2) Greek ano teleia (H2L)ClO4 Greek ano teleia 3H(2)O (1) and [CuL2] (2), where L is the monoanionic form of N '-(1-(pyridin-2-yl)ethylidene)isonicotinohydrazide (HL), have been prepared and characterized by elemental analyses, IR, and single crystal X-ray crystallographic determination. Compound 1 contains a [Cu(HL)(2)](2+) complex cation, a H2L+ cation, three perchlorate anions, and three water molecules of crystallization. Compound 2 contains one neutral [CuL2] complex molecule. The Cu atoms in the complexes are in octahedral coordination, with the hydrazone ligands coordinate to the Cu atoms through the pyridine N, imine N, and enolate O atoms. The effect of the compounds on the antimicrobial activity against Staphylococcus aureus, Escherichia coli, and Candida albicans was studied.