A resource of targeted mutant mouse lines for 5,061 genes

Marie-Christine Birling,Atsushi Yoshiki,David J. Adams,Shinya Ayabe,Arthur L. Beaudet,Joanna Bottomley,Allan Bradley,Steve D. M. Brown,Antje Bürger,Wendy Bushell,Francesco Chiani,Hsian-Jean Genie Chin,Skevoulla Christou,Gemma F. Codner,Francesco J. DeMayo,Mary E. Dickinson,Brendan Doe,Leah Rae Donahue,Martin D. Fray,Alessia Gambadoro,Xiang Gao,Marina Gertsenstein,Alba Gomez-Segura,Leslie O. Goodwin,Jason D. Heaney,Yann Hérault,Martin Hrabe de Angelis,Si-Tse Jiang,Monica J. Justice,Petr Kasparek,Ruairidh E. King,Ralf Kühn,Ho Lee,Young Jae Lee,Zhiwei Liu,K. C. Kent Lloyd,Isabel Lorenzo,Ann-Marie Mallon,Colin McKerlie,Terrence F. Meehan,Violeta Munoz Fuentes,Stuart Newman,Lauryl M. J. Nutter,Goo Taeg Oh,Guillaume Pavlovic,Ramiro Ramirez-Solis,Barry Rosen,Edward J. Ryder,Luis A. Santos,Joel Schick,John R. Seavitt,Radislav Sedlacek,Claudia Seisenberger,Je Kyung Seong,William C. Skarnes,Tania Sorg,Karen P. Steel,Masaru Tamura,Glauco P. Tocchini-Valentini,Chi-Kuang Leo Wang,Hannah Wardle-Jones,Marie Wattenhofer-Donzé,Sara Wells,Michael V. Wiles,Brandon J. Willis,Joshua A. Wood,Wolfgang Wurst,Ying Xu,Juan J. Gallegos,Lydia Teboul,Stephen A. Murray

NATURE GENETICS（2021）

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摘要

The International Mouse Phenotyping Consortium reports the generation of new mouse mutant strains for more than 5,000 genes, including 2,850 novel null, 2,987 novel conditional-ready and 4,433 novel reporter alleles.

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关键词

mutant mouse lines,genes,targeted

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