Unusual mechanical failures of intrathecal baclofen pump systems: symptoms, signs, and trouble shooting

CHILDS NERVOUS SYSTEM(2021)

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摘要
Introduction Although intrathecal baclofen (ITB) therapy is an effective treatment for spasticity, it has several disadvantages and a risk of complications. Methods We present six pediatric patients who suffered from unusual mechanical failures of intrathecal baclofen pump systems. Results With these case-vignettes, we provide a systematic approach on how to interpret the symptoms of ITB complications and an advice which further diagnostic and therapeutic steps to follow. We underline the seriousness of baclofen overdose, underdosing or withdrawal.
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关键词
Intrathecal baclofen therapy, Baclofen pump complication, Baclofen withdrawal, Baclofen overdose, Spasticity, Cerebral palsy, Bisphosphonate therapy
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