Appendoscopy in patients with serrated polyposis syndrome

We read with great interest the study by McKay et al highlighting the topic of appendiceal involvement in patients with serrated polyposis syndrome (SPS).1 Considering a 68% prevalence of serrated lesions of the appendix in a series of 34 patients with SPS treated by colectomy,2 and the difficulty of ruling out an invasion of the appendiceal lumen in case of periappendiceal serrated lesions, the authors advocated prophylactic appendectomy in patients with SPS.\n\nSPS is the most frequent polyposis syndrome, with a prevalence of 0.42% in primary screening cohorts.3 While surgery remains needed for a third of the patients at inception due to the presence of an adenocarcinoma or a lesion burden not amenable …