Single-Domain Multiferroic Array-Addressable Terfenol-D (Smart) Micromagnets For Programmable Single-Cell Capture And Release
ADVANCED MATERIALS(2021)
摘要
Programming magnetic fields with microscale control can enable automation at the scale of single cells approximate to 10 mu m. Most magnetic materials provide a consistent magnetic field over time but the direction or field strength at the microscale is not easily modulated. However, magnetostrictive materials, when coupled with ferroelectric material (i.e., strain-mediated multiferroics), can undergo magnetization reorientation due to voltage-induced strain, promising refined control of magnetization at the micrometer-scale. This work demonstrates the largest single-domain microstructures (20 mu m) of Terfenol-D (Tb0.3Dy0.7Fe1.92), a material that has the highest magnetostrictive strain of any known soft magnetoelastic material. These Terfenol-D microstructures enable controlled localization of magnetic beads with sub-micrometer precision. Magnetically labeled cells are captured by the field gradients generated from the single-domain microstructures without an external magnetic field. The magnetic state on these microstructures is switched through voltage-induced strain, as a result of the strain-mediated converse magnetoelectric effect, to release individual cells using a multiferroic approach. These electronically addressable micromagnets pave the way for parallelized multiferroics-based single-cell sorting under digital control for biotechnology applications.
更多查看译文
关键词
magnetoelastic materials, multiferroics, single‐, cell separation, single‐, domain materials, Terfenol‐, D
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要