MALT-1 inhibition attenuates the inflammatory response of ankylosing spondylitis by targeting NF-κB activation

Hu Qin,Tao Wu,Jun Liu,Gang Wang,Lei Fan,Boyao Wang,Yajun Shen

Injury（2021）

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摘要

•The mRNA and protein levels of MALT1 were increased in the PGIA mouse model.•The treatment of shMALT-1 suppressed the levels of CYLD and NF-κB in the joint tissues.•The inhibition of MALT-1 suppressed the inflammatory response.

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关键词

Ankylosing Spondylitis,Arthritis,Inflammation,NF-κB activation,MALT-1

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