Method of Tumor Pathological Micronecrosis Quantification Via Deep Learning From Label Fuzzy Proportions

The presence of necrosis is associated with tumor progression and patient outcomes in many cancers, but existing analyses rarely adopt quantitative methods because the manual quantification of histopathological features is too expensive. We aim to accurately identify necrotic regions on hematoxylin and eosin (HE)–stained slides and to calculate the ratio of necrosis with minimal annotations ...