Harnessing developmental plasticity to pattern kidney organoids.
Cell stem cell（2021）
摘要
Methods for deriving the ureteric epithelium (UE) in vitro could improve understanding of kidney development and patterning. In this issue of Cell Stem Cell, Howden et al. (2021) identified transcriptionally distinct cell populations in human induced pluripotent stem cell (iPSC)-derived distal nephron (DN) epithelia that were inducible to UE phenotype within kidney organoids.
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