Rapid size-exclusion high performance liquid chromatography method for the quality control of amyloid-β oligomers

Igor Camargo Fontana,Pâmela Cristina Lukasewicz Ferreira,Diogo Miron,Luis Eduardo Santos,Sergio T. Ferreira,Diogo Onofre Souza,Grace Gosmann,Eduardo R. Zimmer,Aline Rigon Zimmer

Journal of Chromatography A（2021）

引用 3|浏览15

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摘要

18•Highly reproducible SE-HPLC method for AβOs quality control.18•High sodium phosphate concentration in the mobile phase decreases peak resolution.18•High oven temperature affects AβOs aggregation.

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关键词

Amyloid-β,Oligomers,SEC-HPLC,Quality control,Validation

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